
Fragrances or perfumes are complex mixtures that may contain hundreds of different ingredients. Many of these ingredients can cause skin allergies, skin irritations, or even affect the respiratory system. In 1999, the European Commission identified 26 fragrance allergens with a high potential to cause allergies, and for which information should be provided to consumers about their presence in cosmetic products. These 26 allergens must be labelled on product packaging once they exceed certain concentration thresholds. However, it can be difficult to completely avoid perfumes that cause allergic reactions, and reactions can range from mild to severe.
| Characteristics | Values |
|---|---|
| Number of fragrance ingredients used in perfumes | More than 2,500 |
| Common problems with fragrance ingredients | Skin allergies, skin irritations, rashes, itching |
| Number of fragrance allergens regulated in the EU | 26 |
| Labelling requirements | Required using the INCI name on the product's ingredients list |
| Additional substances prohibited in the EU | Lyral (Hydroxyisohexyl 3-cyclohexene carboxaldehyde) |
| Number of common fragrances and fragrance markers for patch testing | 41 |
| General level of exposure tolerated by most consumers | Up to 0.8µg/cm2 (0.01% in cosmetic products) |
| Labelling requirements in India | Manufacturers must declare all ingredients, including those with concentrations of less than 1% |
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What You'll Learn

The EU's list of 26 allergens that must be labelled
Perfumes and cosmetics are known to cause skin allergies and irritations. Fragrances are complex mixtures that may contain hundreds of different fragrance ingredients. In 1999, the European Commission published a list of 26 fragrance allergens with a recognised potential to cause allergies. These 26 allergens must be labelled on product packaging when they exceed certain concentration thresholds. The list was published following safety assessments conducted by the Scientific Committee on Cosmetic Products and Non-Food Products (SCCNFP). The goal was to identify the materials with the highest prevalence of allergic sensitization in patch test data and clinical practice.
The 26 allergens must be labelled using the INCI (International Nomenclature of Cosmetic Ingredients) name on the product's ingredients list. This labelling allows consumers with known sensitivities to make informed choices and reduce their exposure to skin sensitizers. It is also important to note that, in addition to the 26 allergens, the European cosmetic regulation maintains an extensive Annex II, listing over 1,300 substances prohibited in cosmetic formulations.
The majority of reactions people endure are simply perfume sensitivities. A true perfume allergy happens when an organic protein in a perfume ingredient causes the reaction. Allergens are technically proteins that the body reacts to with an inflammatory response that causes allergy symptoms. Symptoms of a true perfume allergy include an itchy red rash that appears quickly after exposure to the perfume. Mild symptoms can last for a few weeks even after brief exposure.
To avoid allergic reactions, it is recommended to choose perfumes with minimal ingredients and to avoid common areas where people wearing perfume may walk by. It is also important to let others know about your allergies and to use unscented products to minimise exposure to triggers.
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How to identify a perfume allergy
It can be challenging to identify a perfume allergy, as fragrance manufacturers are not required to list all the chemicals used in their products on the packaging. This makes it difficult to pinpoint the exact cause of an allergic reaction. However, there are some steps you can take to identify and manage a perfume allergy:
Understand the difference between allergy and sensitivity
It is important to distinguish between a true perfume allergy and a sensitivity. A true perfume allergy occurs when your body has an immune system response to an organic protein in a perfume ingredient, causing an inflammatory reaction. On the other hand, sensitivity is much more common and involves a reaction to something that irritates your body without triggering a full-body immune response. With a sensitivity, you may experience a rash that goes away after a few hours or mild symptoms such as a headache or sneezing.
Identify common symptoms
Typical symptoms of a perfume allergy include an itchy red rash that may appear on the skin of the face, hands, or armpits. This rash is often itchy and can last for several weeks. Other mild symptoms may include itching without a visible rash, while more severe reactions may include swelling in the mouth, lips, or tongue, and anaphylaxis, which requires immediate medical attention.
Consult a medical professional
If you suspect you have a perfume allergy, consider consulting an allergist or your doctor. They can perform patch tests that expose you to small amounts of different allergens to determine your specific triggers. An allergist can also confirm the diagnosis and provide guidance on managing your allergy.
Understand labelling practices
While fragrance manufacturers are not required to list all chemicals, there are regulations in place for labelling certain allergens. For example, the European Union has identified 26 specific fragrance allergens that must be labelled on product packaging once they exceed certain concentration thresholds. Understanding these labelling practices can help you identify products containing common allergens and make more informed choices.
Take control of your environment
If you have identified a perfume allergy, it is important to minimise your exposure to triggers. Communicate your allergy to those around you and avoid common areas where people wearing perfume may be present. Additionally, avoid using any scented products yourself, including candles and air fresheners, to reduce your chances of exposure.
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Allergic reactions vs. sensitivities
Perfumes and cosmetics are often fragranced using complex mixtures that may contain hundreds of different ingredients. Many of these ingredients have been known to cause skin allergies, skin irritations, and allergic reactions.
In 1999, the European Commission published a list of 26 fragrance allergens with a well-recognised potential to cause allergies. The presence of these 26 allergens must be indicated in the list of ingredients of a product when their concentration exceeds 0.01% in leave-on products and 0.1% in rinse-off products. This allows consumers who are allergic to one or more of these chemicals to avoid products containing them.
However, it is not mandatory for manufacturers to list all the chemicals used in their perfumes on the product packaging. This can make it difficult for consumers to identify the ingredients that they are allergic to or sensitive to.
An allergy is an abnormal immune reaction to ordinarily harmless substances in fragranced products. When an individual is allergic to a fragrance ingredient, their body identifies the ingredient as a foreign substance and releases an inflammatory reaction to fight it off. This immune system response usually develops over a few days and manifests as itchiness or a rash. These symptoms can last for weeks. A true perfume allergy occurs when an organic protein in a perfume ingredient causes the reaction.
On the other hand, sensitivity is much more common and is a reaction to something that irritates the body. A sensitivity does not trigger a body-wide immune system response. With a sensitivity, an individual might experience a rash that goes away after a few hours, a mild headache, or they might sneeze a few times before the symptoms go away. This is because the body reacts by getting rid of the irritant to return to normal.
While it is difficult to totally avoid perfumes that cause allergic reactions, choosing a perfume with minimal ingredients can reduce the chance of having an allergic or sensitivity reaction.
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Reducing exposure to perfume allergens
While it can be difficult to completely avoid perfumes that cause allergic reactions, there are ways to reduce your exposure to perfume allergens.
Firstly, it is important to understand the difference between an allergy and a sensitivity. Allergens are organic proteins that cause an inflammatory response in the body, resulting in allergy symptoms. On the other hand, sensitivities are more common and are reactions to irritants in the perfume. Understanding which one you are experiencing can help guide your next steps.
If you are experiencing a sensitivity, choosing perfumes with minimal ingredients can reduce the chance of a reaction. You can also try to avoid common areas where people wearing perfume may walk by and trigger your sensitivities.
If you are experiencing an allergy, it is crucial to identify the specific allergen causing the reaction. You can do this by undergoing a patch test with a physician. Once you know the allergen, you can avoid perfumes that contain that ingredient. You can also try natural, plant-based perfumes to achieve a similar scent without the allergens.
To reduce exposure to perfume allergens in general, you can use air purifiers with HEPA filters, which have been shown to reduce aerosolized chemicals and allergens. Letting people around you know about your allergies can also help them take steps to avoid wearing perfume around you. Additionally, avoiding all scented products, including candles and air fresheners, can minimize your exposure to potential triggers.
It is important to note that even products labeled "unscented" or "fragrance-free" may still contain fragrance components, so be cautious when choosing such products.
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The impact on respiratory health
Perfumes and fragrances are a common feature of many household products, from air fresheners to detergents and cosmetics. They are designed to give off a pleasant smell, but for some, they can cause skin allergies and irritation.
The impact of perfumes on respiratory health is a complex issue. Firstly, it is important to distinguish between allergies and sensitivities. A true perfume allergy occurs when an organic protein in a perfume ingredient causes an inflammatory response from the body's immune system. This is different from a sensitivity, which is a reaction to an irritant and does not trigger a full immune response. In the case of allergies, symptoms can last for weeks, whereas sensitivities may cause a rash that goes away within a few hours.
Perfumes and fragrances can contain Volatile Organic Compounds (VOCs), which can irritate and disrupt our airways. When we inhale fragrances, we are breathing in particles that can enter our bloodstream. This can cause a range of reactions, including itchy and watery eyes, congestion, a runny nose, throat irritation, coughing, and wheezing. These reactions are more common in people with pre-existing respiratory conditions, such as asthma or COPD. For example, a 2018 study found asthma-causing chemicals in African American hair products. Fragrances can also contain endocrine-disrupting chemicals, with higher levels found in Black women and children, potentially due to exposure to toxic chemicals in hair products.
While the toxicology of fragrance materials is generally well understood, and most are considered benign, some fragrances can cause adverse health effects, including allergic contact dermatitis. The Steinemann surveys found a causal relationship between fragrance exposure and reported health effects, including respiratory issues. However, other studies, such as one by Maier et al. in 2014, suggest that adverse reactions are more likely due to airway irritation rather than allergic sensitization. This conclusion is supported by Folletti et al. in 2017, who found that household cleaning products could induce or exacerbate respiratory reactions in people with asthma due to airway irritation.
To mitigate the impact of perfumes on respiratory health, individuals can take several measures. For those with allergies or sensitivities, it is essential to avoid common areas where fragranced products may be prevalent. Using air purifiers, wearing masks, and reducing exposure time can also help minimize symptoms. For severe cases, individuals can consider contact allergen testing to identify specific triggers and manage their environment accordingly.
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Frequently asked questions
No. However, there is a list of 26 fragrance allergens that are subject to individual labelling. These allergens must be labelled on product packaging once they exceed certain concentration thresholds.
Allergic reactions can range in severity, but may include hives, itchy skin, a rash, flaking or peeling skin, facial swelling, irritation of the eyes, nose and mouth, wheezing, and anaphylaxis. Anaphylaxis is a severe allergic reaction that can be life-threatening. Symptoms of anaphylaxis include a lack of consciousness, shortness of breath, trouble swallowing, lightheadedness, chest pain, a rapid, weak pulse, nausea, and vomiting.
You can try to avoid common areas where people wearing perfume may walk by and trigger your allergies. You can also keep a small air purifier near your workspace to help keep your air free of airborne proteins that can trigger your symptoms.











































