Seamus Hammond
Hexanol is an organic alcohol with a six-carbon chain and is used in the perfume industry. It is produced industrially by the oligomerization of ethylene. It is believed to be a component of the odour of freshly mown grass and is partly responsible for the fragrance of strawberries. Hexanol is also found in decorative cosmetics, fine fragrances, shampoos, soaps, and toiletries. Phenyl hexanol, also known as phenoxanol, is a synthetic floral ingredient with a rose-muguet character and is used in fine fragrances.
| Characteristics | Values |
|---|---|
| IUPAC Name | Hexan-1-ol |
| Formula | CH3(CH2)5OH |
| State | Colourless liquid |
| Solubility | Slightly soluble in water, miscible with diethyl ether and ethanol |
| Isomers | 2-hexanol and 3-hexanol |
| Odor | Freshly mown grass, strawberries |
| Fragrance | Winey, fatty, fruity, wine-like |
| Synthetic Variant | Phenyl Hexanol (Phenoxanol) |
| Phenyl Hexanol Characteristics | Floral, rose-muguet, soft olfactory intensity, persistent |
| Uses | Perfumes, decorative cosmetics, shampoos, soaps, household cleaners, detergents |
| Safety | No evidence of skin irritation at concentrations of 2-10%, may cause eye irritation undiluted, weak inducer of liver tumors in female mice |
Explore related products
$9.99 $12.99
What You'll Learn
Hexanol is a colourless liquid with a winey, fruity fragrance
Hexanol is a colourless liquid with a distinctive winey, fruity fragrance. It is an organic alcohol with a six-carbon chain and the condensed structural formula CH3(CH2)5OH. It is slightly soluble in water but can be easily mixed with diethyl ether and ethanol.
Hexanol is used in the perfume industry to impart its unique scent. It is also believed to be a component of the odour of freshly mown grass and is partly responsible for the fragrance of strawberries. In addition, alarm pheromones emitted by the Koschevnikov gland of honey bees contain hexanol.
There are different types of hexanol, including 1-hexanol, 2-hexanol, and 3-hexanol, which differ in the location of their hydroxyl groups. Another variety is phenyl hexanol, also known as phenoxanol, a synthetic floral ingredient with a rose-muguet character and subtle green nuances. It is valued for its tenacity and ability to provide a long-lasting floral lift to fine fragrances.
One specific type of hexanol, 2-ethyl-1-hexanol, is commonly used as a fragrance ingredient in decorative cosmetics, fine fragrances, shampoos, soaps, and other toiletries. It is also found in non-cosmetic products like household cleaners and detergents. Studies have been conducted to assess the safety of this variety of hexanol, with no evidence of skin irritation found at certain concentrations.
Choosing the Perfect Perfume as a Gift
You may want to see also
Explore related products
It is used in perfumes, cosmetics, soaps and detergents
Hexanol is an organic alcohol with a six-carbon chain. It is used in the perfume industry and is believed to be a component of the odour of freshly mown grass. It is also partly responsible for the fragrance of strawberries. Hexanol is used in perfumes, cosmetics, soaps, and detergents, adding a winey, fatty, fruity, wine-like note.
One type of hexanol, 2-ethyl-1-hexanol, is a member of the fragrance structural group branched-chain saturated alcohols. It is used in fragrances found in decorative cosmetics, fine fragrances, shampoos, toilet soaps, and other toiletries. It is also used in non-cosmetic products such as household cleaners and detergents. Its use worldwide is in the region of 0.1-1.0 metric tons per annum.
Another type of hexanol, phenyl hexanol (also known as phenoxanol), is a synthetic floral ingredient offering a transparent rose-muguet character with subtle green nuances. It is used for lasting softness in all fragrance types.
Yet another type of hexanol, 1-hexanol, is produced industrially by the oligomerization of ethylene, followed by oxidation of the alkylaluminium products. It is believed to be a component of the odour of honey bees and is partly responsible for the fragrance of strawberries.
Where to Buy Halston Perfume: A Guide
You may want to see also
Explore related products
Hexanol is produced by oligomerization of ethylene
Hexanol, or 1-hexanol, is an organic alcohol with a six-carbon chain and the condensed structural formula CH3(CH2)5OH. It is a colourless liquid that is slightly soluble in water but mixes well with diethyl ether and ethanol. It is used in the perfume industry and has a winey, fruity, coconut, berry-like fragrance. Hexanol is also believed to be a component of the odour of freshly mown grass and is partly responsible for the fragrance of strawberries.
Hexanol is produced industrially by the oligomerization of ethylene using triethylaluminium. This process is followed by the oxidation of alkylaluminium products. An idealized synthesis of this process is shown below:
Al(C2H5)3 + 6C2H4 → Al(C6H13)3
Al(C6H13)3 + 1+1⁄2O2 + 3H2O → 3HOC6H13 + Al(OH)3
The above reactions show the oligomerization of ethylene using triethylaluminium and the subsequent oxidation of the resulting alkylaluminium product to produce hexanol. The process generates a range of oligomers that are then separated by distillation.
Another method to produce hexanol involves the hydroformylation of 1-pentene, followed by the hydrogenation of the resulting aldehydes. This method is used in the industry to produce mixtures of isomeric C6-alcohols, which are precursors to plasticizers.
In principle, 1-hexene could be converted to 1-hexanol by hydroboration (diborane in tetrahydrofuran followed by treatment with hydrogen peroxide and sodium hydroxide). However, this method is primarily useful for laboratory synthesis and not for large-scale production due to the commercial availability of inexpensive 1-hexanol from ethylene.
Molecule 01 Perfume: Where to Buy in Canada
You may want to see also
Explore related products
$8.86
It is a weak inducer of liver tumours in female mice
Hexanol is an organic alcohol with a six-carbon chain. It is a colourless liquid that is slightly soluble in water and is used in the perfume industry. Hexanol is also a component of the odour of freshly mown grass and is partly responsible for the fragrance of strawberries.
While I could not find specific information on hexanol's link to liver tumours in female mice, studies have shown that dietary sugar intake increases liver tumour incidence in female mice. This may be due to the role of estrogen, as ovariectomy increases tumour incidence in female mice, while estrogen treatment of male mice decreases tumour incidence. Additionally, it is suggested that other factors such as adiposity and hepatic fat content may also contribute to the sex discrepancy in tumour development.
In one study, female mice were exposed to the liver carcinogen diethylnitrosamine (DEN) and fed diets with varying sugar and fat content. The results indicated that mice fed diets with high sugar content had the highest incidence of liver tumours, while dietary fat intake did not appear to influence tumour development. This suggests that sugar intake may be a significant factor in the formation of liver tumours in female mice.
Another study found that chemical hepatocarcinogenesis in female mice, induced by 5,9-dimethyl(7H)dibenzo[c,g]carbazole, leads to the overexpression of a specific protein, Cyp2a-5, which is associated with liver tumours. This study also noted that male mice displayed a weak expression of Cyp2a-4 and Cyp2a-5 in control liver samples, but the expression of these proteins increased significantly after castration.
It is important to note that the development of liver tumours is a complex process influenced by various factors, and further research is needed to fully understand the mechanisms involved in tumourigenesis, especially in female subjects.
Fresh Scents: Discovering Clean-Smelling Perfumes
You may want to see also
Explore related products
Phenyl hexanol is a synthetic floral variation
Hexanol is an organic alcohol with a six-carbon chain. It is a colourless liquid that is slightly soluble in water. Hexanol is used in the perfume industry, where it is valued for its winey, fatty, and fruity notes. Hexanol is also a component of the odour of freshly cut grass, and it is partly responsible for the fragrance of strawberries.
Phenyl hexanol, also known as phenoxanol, is a synthetic floral variation of hexanol. It offers a transparent rose-muguet character with subtle green nuances. While it is soft in olfactory intensity, it is persistent and provides a long-lasting floral lift. Its molecular structure gives it greater tenacity than phenylethyl alcohol, making it valuable in fine fragrances, muguet compositions, and floral diffusion systems. Phenyl hexanol is a branched aliphatic alcohol with a phenyl substitution, developed for use as a lasting floral component in modern perfumery. Its scent is evident throughout the evaporation curve, making it a subtle yet effective contributor to a fragrance's body.
Phenyl hexanol is described as having a diffusive, fresh, floral, rose absolute type of odour. It is long-lasting and economical, providing an expensive rose oil or absolute effect. It is used to give freshness and volume to both floral and citrus fragrances. Its scent is not overpowering, but rather, it has been described as petal-like, fresh, and slightly melancholic.
Phenyl hexanol is an effective ingredient in small amounts, yet it can tolerate high dosages, offering both impact and versatility. Its molecular structure and performance characteristics make it a valuable ingredient in perfumery.
How to Neutralize Perfume with Vinegar
You may want to see also
Frequently asked questions
Hexanol is an organic alcohol with a six-carbon chain. It is a colourless liquid that is slightly soluble in water. It is believed to be a component of the odour of freshly cut grass and is partly responsible for the fragrance of strawberries.
Hexanol is used in perfumes to add winey, fatty, fruity notes. It is also used in decorative cosmetics, fine fragrances, shampoos, soaps, and other toiletries. Phenyl hexanol, also known as phenoxanol, is a synthetic floral ingredient that provides a long-lasting floral lift.
According to a review of toxicology and dermatology papers, no evidence of skin irritation was found at concentrations of 2-10%. Eye irritation is also not a concern at current end-product use levels. However, an elicitation reaction is possible for individuals who are already sensitized.
Many perfume companies use hexanol in their fragrances, including Advanced Biotech Inc., Beijing Lys Chemicals Co., Firmenich Inc., and Fleurchem Inc.
