
Synthetic cannabinoids, also known as fake weed, are often sold as herbal incense and smoked as an alternative to marijuana. These products, which have brand names such as Mojo, Spice, and K2, are designed to replicate the effects of marijuana without showing up on drug tests. However, health concerns have been raised about these synthetic cannabinoids, which have been linked to kidney failure and seizures.
| Characteristics | Values |
|---|---|
| Brand names | Spice, K2, Mojo, Cloud 9 |
| Legal status | Legal in Texas, illegal in Kansas |
| Availability | Head shops, corner gas stations, pharmacies, internet |
| Target audience | Employees, students, hardcore drug users |
| Effects | Marijuana-like "high", toxic results |
| Detection in drug tests | Does not show up in company drug tests, DEA trying to replicate it in lab tests |
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What You'll Learn

Synthetic cannabinoids in herbal incense
Synthetic cannabinoids are human-made mind-altering chemicals that are either sprayed on dried, shredded plant material or sold as liquids to be vaporized and inhaled in e-cigarettes or other devices. They are designed to mimic the effects of THC, the psychoactive ingredient in marijuana. These synthetic cannabinoids are often marketed and sold as "herbal incense" or "potpourri" and are abused for their psychoactive properties.
Synthetic cannabinoids were first detected in herbal blends near the end of 2008 and have since become a significant public health concern due to their increasing use, unpredictable toxicity, and abuse potential. They are often labelled "not for human consumption" for liability defence and are sold under various brand names such as "Spice," "K2," "Mojo," and "Cloud 9."
These synthetic cannabinoids can have diverse chemical structures, and their effects can be highly unpredictable. They are known to have a higher binding affinity to cannabinoid receptors, particularly CB1 receptors, which are linked to the psychoactive effects or "high" associated with marijuana use. This increased binding affinity contributes to their higher toxicity compared to natural cannabis.
The adverse health effects associated with the abuse of herbal incense products containing synthetic cannabinoids include an elevated heart rate, high blood pressure, unconsciousness, tremors, seizures, vomiting, hallucinations, agitation, anxiety, pallor, numbness, and tingling. There have been reports of overdoses and severe bleeding caused by contaminated products.
While synthetic cannabinoids might not show up on standard drug tests, it is important to note that their use is not without risks. The unpredictable nature of their effects and the potential presence of unknown contaminants in commercial products can lead to dangerous consequences for users.
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'Spice' and K2 herbal incense blends
"Spice" and "K2" are brand names for synthetic cannabinoids (SCBs) that are often disguised as herbal incense blends. These synthetic cannabinoids were first detected in 2008 and have since become a significant public health concern due to their increasing use, unpredictable toxicity, and abuse potential.
Spice and K2 are typically dissolved in a volatile solvent, such as ethanol or acetone, and then sprayed or mixed with plant leaves such as Indian Warrior, Lion's Ear, Dog Rose, or Marshmallow leaves. These plant leaves are believed to have psychotropic effects when smoked. The mixture is then dried and can be smoked or vaporized, similar to marijuana.
These synthetic cannabinoids produce effects similar to tetrahydrocannabinol (THC) and marijuana by activating cannabinoid receptors CB1R and CB2R. However, unlike THC, which is a partial agonist, SCBs are direct agonists of cannabinoid receptors, leading to higher rates of toxicity and hospital admissions. The chemical structures of SCBs found in Spice or K2 can interact in unpredictable ways, and the products may contain unknown contaminants.
Spice and K2 are often marketed as legal highs or alternatives to marijuana that will not show up on drug tests. While the original compounds found in Spice products have been made illegal, there are currently no drug tests specifically designed to detect synthetic cannabinoids in herbal incense blends. This is because these products are not composed of a single substance, and any laboratory analysis would need to test for a wide range of synthetic marijuana metabolites. However, the Drug Enforcement Agency (DEA) is working on replicating fake weed in lab tests to make it detectable in drug tests.
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Mojo: a synthetic herbal incense
Mojo is a synthetic herbal incense that is becoming an increasingly popular alternative to marijuana. It is also known as fake weed or faux pot. Mojo is legal in the state of Texas, but it is now illegal in Kansas, and Missouri is also considering banning it.
Mojo is created from synthetic cannabinoids, which are human-made chemicals that act on the same brain cell receptors as tetrahydrocannabinol (THC), the primary ingredient in marijuana. Synthetic cannabinoids are often created in laboratories for research purposes. However, they have recently been used recreationally, with names like "Spice", "K2", "Cloud 9", and "Mojo". These synthetic cannabinoids are a growing public health concern due to their increasing use, unpredictable toxicity, and abuse potential. They have been linked to kidney failure and seizures, and their effects can be more potent than natural cannabis.
Mojo is often sold in small packages at head shops, gas stations, and even pharmacies. It is marketed as incense, and while it is supposed to be only sold to adults, underage students have been able to purchase it. Mojo is more expensive than marijuana, with one gram costing around $40. Despite its legality, Mojo is potent and can induce a high similar to marijuana.
The primary reason for Mojo's popularity is that it does not contain THC and, therefore, does not show up on standard drug tests. However, the Drug Enforcement Agency (DEA) is working to replicate fake weed in lab tests so that it can be detected in the future. This is a challenging task, as the chemical structure of synthetic cannabinoids can vary, and the specific compounds in products like Mojo are often unknown, even to the manufacturers.
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Drug discrimination and behavioural techniques
Synthetic cannabinoids, also known as "herbal incense", are becoming a large public health concern due to their increasing use, unpredictable toxicity, and abuse potential. These substances, sold under brand names such as "Spice", "K2", and "Mojo", are designed to mimic the effects of marijuana or THC. While the use of these synthetic cannabinoids does not show up on company drug tests, the DEA is working on replicating them in lab tests so that they can be detected in the future.
In a typical drug discrimination experiment, a behaviour is reinforced based on the presence or absence of a specific drug stimulus. For example, after administering a training dose of a drug, a particular response may be reinforced, such as by exchanging it for money. This technique can be used to study the underlying neuropharmacology of drugs in vivo, providing valuable insights into the effects of drugs on behaviour.
The procedure for drug discrimination experiments typically involves three stages: errorless training, discriminative training, and generalization testing. During errorless training, subjects are administered either a drug or a non-drug before being placed in an operant chamber, where they can respond to receive a reinforcer. Once the subject achieves the desired number of responses, discriminative training begins, where they must respond with a certain degree of accuracy before progressing to the next stage. During generalization testing, the drug dose is altered to create a dose-response curve, which helps determine the threshold at which the subject can no longer distinguish between drug and non-drug conditions.
Overall, drug discrimination and behavioural techniques provide a powerful tool for understanding the subjective effects of drugs and their impact on behaviour. These techniques have been applied to various species, with rats being the most commonly used experimental subject, and have contributed significantly to our knowledge of drug effects and substance use disorders.
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The legality of herbal incense
Herbal incense, also known as synthetic marijuana, is a dangerous trend that is marketed as natural and safe. It is a synthetic cannabinoid that produces effects similar to tetrahydrocannabinol (THC) and marijuana. These synthetic cannabinoids are designed to activate the same receptors in the brain as natural cannabinoids, but they have a significantly more profound impact. The long-term effects of these synthetic cannabinoids are not well understood, as they were initially created for use with animals and cells, not humans.
The popularity of herbal incense has been rising, especially among teens and young adults, as it is often sold as a legal high that does not show up on drug tests. However, the health risks associated with its use are significant, including life-threatening bleeding, kidney failure, seizures, fast heartbeat, severe vomiting, and irritability. In 2011, the Drug Enforcement Administration (DEA) made some common synthetic cannabinoids Schedule 1 drugs, making them illegal to use in the manufacture and sale of herbal drugs. This was in response to the growing number of reported deaths and overdoses from the use of synthetic marijuana.
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Frequently asked questions
Synthetic cannabinoids, commonly known as herbal incense, are designed to not show up on drug tests. However, the DEA is trying to replicate fake weed in lab tests so that it can be detected in the future.
Herbal incense is a synthetic cannabinoid that produces effects similar to tetrahydrocannabinol (THC) and marijuana. It is often sold under brand names such as "Spice", "K2", "Mojo", and "Cloud 9".
People use herbal incense as a way to get high without it showing up on a drug test. It is also easily accessible and can be purchased online or at local head shops, gas stations, and pharmacies.
No, herbal incense is not safe. It has been linked to health concerns such as kidney failure and seizures. The exact contents of herbal incense products are often unknown, and they may contain unknown contaminants.
The legality of herbal incense varies by location. For example, it is legal in Texas but illegal in Kansas. However, it is important to note that just because something is legal does not mean it is safe.











































